Definition of puke

• a person who is deemed to be despicable or contemptible; "only a rotter would do that"; "kill the rat"; "throw the bum out"; "you cowardly little pukes!"; "the British call a contemptible person a `git"
• the matter ejected in vomiting
• eject the contents of the stomach through the mouth; "After drinking too much, the students vomited"; "He purged continuously"; "The patient regurgitated the food we gave him last night"