VACATION
A period of time when you take a break from work or studies to relax or travel (छुट्टी / अवकाश)
We went to Goa for a vacation.
The school will be closed for summer vacation.
VOCATION
A job, profession, or occupation — especially one that you feel specially suited for or called to do (व्यवसाय)
He chose medicine as his vocation.
Everyone should find a vocation that suits their talent.